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Microfluidic Chip Manufacturing

AT-Machining leverages extensive experience in microfluidic chip machining, delivering high-precision devices with intricate microchannel networks and precise surface finishes.

Save 30% Cost on average!

What Is Microfluidic Chip?

Microfluidic chips are miniature devices we precision-manufacture using advanced CNC techniques. These chips contain microscopic channels and chambers that manipulate tiny amounts of fluids for various applications. Our expertise in high-precision machining allows us to create these complex, miniaturized systems for biotechnology, medical diagnostics, and chemical analysis industries, meeting the growing demand for lab-on-a-chip technologies in the global market.

Partner with our precision CNC machining experts to bring your microfluidic chip designs to life. Contact us today and let’s discuss how we can manufacture your high-performance, customized lab-on-a-chip solutions.

How to Manufacturing Microfluidic Chip?

As a CNC machining factory, we excel at manufacturing high-precision microfluidic chips based on our customers’ design drawings. Our advanced machining capabilities allow us to precisely mill the intricate microchannel networks, drill the necessary inlet and outlet ports, and carefully bond the layers together to create the final chip. We follow strict quality control measures to ensure the devices meet the required specifications for their intended biotechnology, medical, or scientific applications.

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CNC Milling

CNC milling in microfluidic chip machining involves precision-milling microchannels and features using high-speed CNC mills with microscale resolution and accuracy.

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CNC Drilling

CNC drilling in microfluidic chip machining creates precise inlet and outlet ports with high-accuracy, ensuring fluid flow and chip functionality.

Material Selection for Microfluidic Chip

  • Polydimethylsiloxane (PDMS): The most popular material for microfluidic devices due to its ease of fabrication, optical transparency, gas permeability, and elastomeric properties. PDMS is ideal for rapid prototyping and is biocompatible and non-toxic.
  • Polymethylmethacrylate (PMMA): Offers low cost, rigid mechanical properties, excellent optical transparency, and compatibility with electrophoresis. PMMA is often used for disposable chips.
  • Polycarbonate (PC) and Polystyrene (PS): These polymers are robust, easy to access, and cheaper than inorganic materials. They are used in various microfluidic applications due to their optical transparency and ease of fabrication.
  • Cyclic Olefin Copolymer (COC) and Polyethylene Glycol Diacrylate (PEGDA): These materials are also widely used for their biocompatibility, transparency, and low cost. They are particularly useful for applications requiring minimal nonspecific adsorption.
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The Applications of Microfluidic Chip

Biomedical

Microfluidic chips enable rapid, accurate, and portable diagnostic tools for detecting diseases like HIV, malaria, and COVID-19, revolutionizing point-of-care diagnostics and healthcare delivery.

Chemical & Biochemical Analysis

Microfluidic chips serve as miniature reactors for performing chemical and biochemical reactions with high efficiency and control over reaction conditions, enabling precise analysis and synthesis.

Life Science Research

Microfluidic chips facilitate single-cell analysis, organ-on-a-chip studies, and controlled cell culture, providing insights into cellular behavior, organ-specific processes, and tissue development.

Environmental Monitoring

Microfluidic devices detect contaminants in water, air, and soil samples, enabling rapid and accurate assessments of environmental quality and contributing to sustainable development and conservation.

Gallery of Our CNC machined Microfluidic Chip

Elevate Your Microfluidic Research with Our Precision Manufacturing Expertise. Contact Us Today for Custom Chip Solutions, Rapid Prototyping, and High-Volume Production.

Tips for Design & Manufacturing Microfluidic Chip

Choose a material that is biocompatible, chemically resistant, and suitable for the intended application, such as PDMS, glass, or polymer, depending on your actual needs.

Design channels with optimal dimensions, shapes, and surface roughness to ensure efficient fluid flow, minimize pressure drops, and prevent clogging.

Design interfaces and connections that are secure, leak-free, and easy to use, such as tubing, fittings, and connectors, to ensure reliable fluid transfer.

Specify manufacturing tolerances that balance precision, cost, and yield, considering factors like channel width, depth, and surface finish.

Perform thorough testing and validation to ensure the microfluidic chip meets performance requirements, including fluid flow, pressure, and functionality.

Transform Your Research with Custom Microfluidic Chips! Contact us today to discuss your project and receive a quote for high-quality, precision-manufactured microfluidic chips tailored to your specific needs

Why Choose AT for Your Microfluidic Chip Manufacturer

Precision CNC Machining

Our advanced CNC machinery ensures microchannels are milled with ±0.002mm accuracy, delivering the highest precision for your microfluidic chips.

Material Expertise

Extensive experience with various materials, including PMMA, PDMS, and glass, ensures optimal chip performance and durability.

Fast Turnaround

Quick production times, with standard lead times of 5-7 business days, enable rapid project completion and accelerated innovation.

Cost-Effective

Competitive pricing, with savings up to 30% compared to traditional methods, makes high-quality microfluidic chips more accessible.

Rapid Prototyping

Prototypes ready in as little as 48 hours, allowing for fast design iterations and accelerated product development.

Quality Assurance

Rigorous quality control, with a 99% yield rate and comprehensive testing, ensures every microfluidic chip meets the highest standards.

FAQs about Microfluidic Chip Manufacturing

Common materials include polydimethylsiloxane (PDMS), polymethylmethacrylate (PMMA), glass, and cyclic olefin copolymer (COC). Each material has unique properties suitable for different applications.

Common methods include CNC milling, photolithography, soft lithography, and injection molding. Each method has its benefits depending on the material and application.

AT-Machining ensures high precision with tolerances as tight as ±0.002mm, critical for the functionality of microfluidic devices

Yes, AT-Machining offers customization capabilities to accommodate various materials and complex geometries, tailoring solutions to meet specific design requirements.

CNC machining offers high precision, repeatability, and the ability to work with a wide range of materials, making it ideal for microfluidic chip manufacturing.